Tonight, we are broadcasting from New York City.

The man who was a suspect in the disappearance of his wife turned on the gas in his home-ignited it-and blew up the house, himself and the couple's two children. The tragedy comes just days after he was denied custody of the kids and ordered to undergo a psycho-sexual examination. Dr. Drew and his guests ask 'why,' and examine the note he left his attorney.

Then, citizens of Le Roy, New York sound off in a town meeting over the weekend. Will their anger get them the answers they demand about the tics and twitches suffered by a cluster of residents? We've got the latest. For the first time, you'll see Dr. Drew sitting down on set with parents whose daughters are suffering from the sudden tics and twitches.

Watch Dr. Drew tonight and every weeknight at 9 on HLN.